epsilon-CAPROLACTONE → D,D-Dilactide
Reaction equation
[CH3:1][C@@H:2]1[O:9][C:7](=[O:8])[C@H:6]([CH3:10])[O:5][C:3]1=[O:4].C1(=O)OCCCCC1>CCCCC(C([O-])=O)CC.CCCCC(C([O-])=O)CC.[Sn+2]>[CH3:1][C@H:2]1[O:9][C:7](=[O:8])[C@@H:6]([CH3:10])[O:5][C:3]1=[O:4]Participants
4
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 150 °C
Procedure
An amorphous, non-crystallizable copolymer of 80 mol. % L-lactide and 20 mol. % D-lactide was prepared by ring-opening polymerisation in the melt, in the presence of 0.1% by weight tin octoate as catalyst. To this polymer was added an amount of 20% by weight of ε-caprolactone, whereafter, under nitrogen and with continuous mechanical stirring, the mixture was heated to 150° C. To the homogeneous mixture, again 0.1% by weight tin octoate as catalyst was added, whereafter the polymerisation was completed.
Sources & evidence
- ORD record
- ord-19110a7bb1be46349de6df1eacabbfa2
- Source dataset
- uspto-grants-1997_09
- Patent number
- US05672367
Reaction notes
Loading…