Acetic acid, 2-oxo-, methyl ester → HCID 23327043, compound

HRID 1379983Notes

Reaction equation

HRID 1379983 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=1)[C:6]([NH2:8])=[O:7].[C:12]([O:16][CH3:17])(=[O:15])[CH:13]=[O:14]>C1(C)C=CC=CC=1>[CH3:17][O:16][C:12](=[O:15])[CH2:13][O:14][NH:8][C:6](=[O:7])[C:5]1[CH:9]=[CH:10][CH:11]=[C:3]([O:2][CH3:1])[CH:4]=1

Participants

4

Reactant 2

HCID 70205Acetic acid, 2-oxo-, methyl esterHCID 984873-Methoxybenzamide

Product 1

HCID 23327043HCID 23327043, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

3-Methoxybenzamide (13.25 g) and methyl glyoxylate (7.72 g) in toluene (150 ml) were heated under reflux in a Dean-Stark apparatus for 6 hours. On cooling the mixture the product separated and was crystallised from toluene. Yield, 12.0 g, m.p. 93°-94°.

Workup

  1. temperatureunder reflux in a Dean-Stark apparatus for 6 hours
  2. temperatureOn cooling the mixture the product
  3. customseparated
  4. customwas crystallised from toluene
  5. customYield

Sources & evidence

ORD record
ord-76c714444ef64230a1065be1a2126181
Source dataset
uspto-grants-1986_04
Patent number
US04579581

Reaction notes

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