反应详情

3-Methoxybenzamide (13.25 g) and methyl glyoxylate (7.72 g) in toluene (150 ml) were heated under reflux in a Dean-Stark apparatus for 6 hours. On cooling the mixture the product separated and was crystallised from toluene. Yield, 12.0 g, m.p. 93°-94°.

1. temperatureunder reflux in a Dean-Stark apparatus for 6 hours
2. temperatureOn cooling the mixture the product
3. customseparated
4. customwas crystallised from toluene
5. customYield