反应详情

To a suspension of 3-[(2-benzothiazolyl)methoxy]nitrobenzene (18.6 g) in ethanolic hydrochloric acid is added powdered iron. The reaction is stirred overnight at room temperature. After neutralization with saturated aqueous sodium bicarbonate, the mixture is extracted three times with methylene chloride. The extract is dried over magensium sulfate and concentrated to give 15.1 g (90% yield) of product, m.p. 117°-120° C.

1. additionis added
2. extractionAfter neutralization with saturated aqueous sodium bicarbonate, the mixture is extracted three times with methylene chloride
3. dry with materialThe extract is dried over magensium sulfate
4. concentrationconcentrated