HCID 23325188, compound → 103451-26-9

HRID 1380484Notes

Reaction equation

HRID 1380484 reaction equation
[ClH:1].[NH2:2][CH:3]([C:11]#[CH:12])[CH2:4][CH2:5][C:6]([O:8]CC)=[O:7]>Cl>[ClH:1].[NH2:2][CH:3]([C:11]#[CH:12])[CH2:4][CH2:5][C:6]([OH:8])=[O:7]

Participants

3

Reactant 1

HCID 23325188HCID 23325188, compound

Product 1

HCID 86740723103451-26-9

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of 0.4 g of 1 in 2 ml of concentrated hydrochloric acid was stirred at room temperature for one hour. The water was evaporated. Toluene was added to the residue and distilled to remove residual water by azeotropic distillation. The residue was dried under reduced pressure to give 2, as a hygroscopic solid.

Workup

  1. customThe water was evaporated
  2. additionToluene was added to the residue
  3. distillationdistilled
  4. customto remove residual water
  5. distillationby azeotropic distillation
  6. customThe residue was dried under reduced pressure
  7. customto give 2

Sources & evidence

ORD record
ord-120eef4f41cc4363a087d5da0525a238
Source dataset
uspto-grants-1986_04
Patent number
US04582529

Reaction notes

Loading…