反应详情

Reflux 91.3 g of the aldehyde of Step D, 27.4 g of hydroxylamine hydrochloride and 41.9 g of sodium formate in 900 ml of formic acid (98-100%) for 11/4 hours. Cool the mixture and pour into 21/2 liters of cold water. Separate the precipitate, wash with water and dry in vacuo at 75° C. (Yield: 82 g).

1. temperatureCool the mixture
2. customSeparate the precipitate
3. washwash with water
4. customdry in vacuo at 75° C. (Yield: 82 g)