Acrylic Acid → N-(3-(Dimethylamino)-2,2-dimethylpropyl)acrylamide

HRID 1380699Notes

Reaction equation

HRID 1380699 reaction equation
[CH3:1][N:2]([CH3:9])[CH2:3][C:4]([CH3:8])([CH3:7])[CH2:5][NH2:6].[C:10](O)(=[O:13])[CH:11]=[CH2:12]>B(F)(F)F>[CH3:1][N:2]([CH3:9])[CH2:3][C:4]([CH3:8])([CH3:7])[CH2:5][NH:6][C:10](=[O:13])[CH:11]=[CH2:12]

Participants

4

Reactant 2

HCID 6581Acrylic AcidHCID 104477N,N,2,2-Tetramethylpropane-1,3-diamine

Product 1

HCID 88388N-(3-(Dimethylamino)-2,2-dimethylpropyl)acrylamideYield 72%

Reagents, catalysts & solvents 1

HCID 6356Boron trifluorideSolvent

Procedure

Proceeding as in Example 1, 260 g 3-dimethylamino-2,2-dimethylpropylamine; 144 g acrylic acid; 4 g N,N'-diphenylenediamine; and 10 ml BF3-etherate were mixed. It was found possible to isolate 265 g (72%) of the N-(3-dimethylamino-2,2-dimethylpropyl)acrylamide.

Sources & evidence

ORD record
ord-dc934397b71e4fc6b0ef80d07587b4e8
Source dataset
uspto-grants-1986_04
Patent number
US04582933

Reaction notes

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