Dimethylformamide → tert-Butyl 2-fluoro-4-formylbenzoate

HRID 138076Notes

Reaction equation

HRID 138076 reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:15])[c:5]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[cH:13][cH:14]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:16][CH2:17][CH2:18][CH2:19][Li:20].[O:21]=[CH:22][N:23]([CH3:24])[CH3:25]>>[c:2]1([CH:22]=[O:21])[cH:3][c:4]([F:15])[c:5]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[cH:13][cH:14]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 46738774tert-Butyl 4-bromo-2-fluorobenzoateHCID 178418339Butyllithium

Product 1

HCID 86607392tert-Butyl 2-fluoro-4-formylbenzoate

Sources & evidence

ORD record
ord-7e6590bfae164dc8af0a4fc7bfa855d3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…