Hydrochloric Acid → HCID 12330040, compound

HRID 1381242Notes

Reaction equation

HRID 1381242 reaction equation
[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][O:5][C:4]2[CH:13]=[CH:14][C:15]([CH2:17][C:18]([O:20][CH3:21])=[O:19])=[CH:16][C:3]1=2.[BH4-].[Na+].Cl.[CH3:25]O>>[CH3:25][O:1][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH2:6][O:5][C:4]2[CH:13]=[CH:14][C:15]([CH2:17][C:18]([O:20][CH3:21])=[O:19])=[CH:16][C:3]1=2

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 4311764Sodium borohydrideHCID 10333952Methyl (11-oxo-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetate

Product 1

HCID 12330040HCID 12330040, compound

Procedure

A mixture of 5.64 g. of methyl 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetate, 0.4 g. of sodium borohydride and 250 ml. of methanol is stirred at 0°-2° for four hours. The reaction product is treated with 1 N hydrochloric acid and extracted with chloroform, and the chloroform extracts are washed with saturated sodium bicarbonate solution and dried with sodium sulfate. The chloroform is evaporated to leave methyl 6, 11-dihydro-11-methoxydibenz[b,e]oxepin-2-acetate as an oil;

Workup

  1. additionA mixture of 5.64 g
  2. extractionextracted with chloroform
  3. washthe chloroform extracts are washed with saturated sodium bicarbonate solution
  4. dry with materialdried with sodium sulfate
  5. customThe chloroform is evaporated

Sources & evidence

ORD record
ord-baf9bfc5120c474fa0433c1a4af697f4
Source dataset
uspto-grants-1986_04
Patent number
US04585788

Reaction notes

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