Hydrochloric Acid → Glycinamide

HRID 138128Notes

Reaction equation

HRID 138128 reaction equation
[C:1]([O:2][C:3]([CH3:4])([CH3:5])[CH3:6])(=[O:7])[NH:8][CH2:9][C:10](=[O:11])[NH2:12].[CH3:45][CH2:46][O:47][CH2:48][CH3:49].[Cl:50][CH2:51][Cl:52].[ClH:38].[NH2:13][c:14]1[cH:15][c:16]([CH:22]=[C:23]([C:24]#[N:25])[c:26]2[cH:27][c:28]([O:36][CH3:37])[c:29]([O:34][CH3:35])[c:30]([O:32][CH3:33])[cH:31]2)[cH:17][cH:18][c:19]1[O:20][CH3:21].[O:39]1[CH2:40][CH2:41][O:42][CH2:43][CH2:44]1>>[NH2:13][c:14]1[cH:15][c:16]([CH:22]=[C:23]([C:24]#[N:25])[c:26]2[cH:27][c:28]([O:36][CH3:37])[c:29]([O:34][CH3:35])[c:30]([O:32][CH3:33])[cH:31]2)[cH:17][cH:18][c:19]1[O:20][CH3:21].[NH2:8][CH2:9][C:10](=[O:11])[NH2:12]

Participants

8

Reactant 6

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 109100641,1-Dimethylethyl N-(2-amino-2-oxoethyl)carbamateHCID 541022033-(3-Amino-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)prop-2-enenitrile

Product 2

HCID 69020GlycinamideHCID 541022033-(3-Amino-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)prop-2-enenitrile

Sources & evidence

ORD record
ord-095427fbe4994d7ea4047515aac4d379
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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