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HRID1381967

反应详情

EQUATION

反应方程式

HRID 1381967 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)N[C@H]1[C@H](O[C@@H]([C@H](O)[C@H](C=O)NC(C)=O)[C@H](O)CO)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@@H]1O
HCID123774

2-Deoxy-2-[(1-hydroxyethylidene)amino]hexopyranosyl-(1->4)-2-deoxy-2-[(1-hydroxyethylidene)amino]hexopyranosyl-(1->4)-2-deoxy-2-[(1-hydroxyethylidene)amino]hexose

C24H41N3O16

结构：CC(=O)N[C@H]1[C@H](O[C@@H]([C@H](O)[C@H](C=O)NC(C)=O)[C@H](O)CO)O[C@H](CO)[C@@H](O)[C@@H]1O
HCID160244

2-Deoxy-4-O-{2-deoxy-2-[(1-hydroxyethylidene)amino]hexopyranosyl}-2-[(1-hydroxyethylidene)amino]hexose

C16H28N2O11

结构：CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
HCID439174

N-Acetylglucosamine cyclized form

C8H15NO6

PRODUCTS

生成物

1
结构：CC(=O)N[C@H]1[C@H](O[C@@H]([C@H](O)[C@H](C=O)NC(C)=O)[C@H](O)CO)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5NC(C)=O)[C@H](O)[C@H]4NC(C)=O)[C@H](O)[C@H]3NC(C)=O)[C@H](O)[C@H]2NC(C)=O)[C@@H]1O
HCID197182

N-Acetylchitohexaose

C48H80N6O31

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

The combined effluent fractions were freeze-dried to give 36 g of a solid mixture comprising tetra-N-acetylchitotetraose (NACOS-4), penta-N-acetyl-chitopentaose (NACOS-5) and hexa-N-acetyl-chitohexaose (NACOS-6), together with minor proportions of N-acetylglucosamine, di-N-acetyl-chitobiose, tri-N-acetyl-chitotriose. This mixture comprising the water-soluble chitin-oligomers was then chromatographed by a high pressure liquid chromatography on a column of μ-Bondapack CH (a product of Waters Company, U.S.A.) as eluted with methylnitrile-water (70:30 by volume), to effect the isolation of the chitin-oligomers from each other, affording 3.10 g of hexa-N-acetylchitohexaose having an [α]D of -11.2° and a decomposition temperature of 300° C., 7.6 g of penta-N-acetyl-chitopentaose having an [α]D of -9.0° and a decompsition temperature of 304° C.; and 8.1 g of tetra-N-acetyl-chitotetraose having an [α]D of -4.2° and a decomposition temperature of 299° C.

WORKUP

后处理

  1. customwas then chromatographed by a high pressure liquid chromatography on a column of μ-Bondapack CH (a product of Waters Company, U.S.A
  2. wash) as eluted with methylnitrile-water (70:30 by volume)