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HRID1381998

反应详情

EQUATION

反应方程式

HRID 1381998 的结构方程式

REACTANTS

反应物

2
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：CCOC(=O)CCNC=C(C(=O)OCC)C(=O)c1cc(F)c(Cl)c([N+](=O)[O-])c1Cl
HCID178472018

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1cnc2c([N+](=O)[O-])c(Cl)c(F)cc2c1O
HCID178469671

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

52 g of the product from Example 4 and 18.5 g of K2CO3 are heated at 140° C. for 4 hours in 160 ml of DMF. The mixture is subsequently poured onto ice and acidified, and the precipitated solid is isolated. It is dried and recrystallized from glycol methyl ether acetate. Yield: 35.8 g, melting point: 226°-8° C. (decomposes).

WORKUP

后处理

  1. additionThe mixture is subsequently poured onto ice
  2. customthe precipitated solid is isolated
  3. customIt is dried
  4. customrecrystallized from glycol methyl ether acetate