Benzonitrile, 4-bromo- → HCID 19786992, compound

HRID 1382425Notes

Reaction equation

HRID 1382425 reaction equation
[CH3:1][C:2]1[C:3]([C:14]#[CH:15])=[CH:4][C:5]2[C:6]([CH3:13])([CH3:12])[CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1.Br[C:17]1[CH:24]=[CH:23][C:20]([C:21]#[N:22])=[CH:19][CH:18]=1>>[CH3:1][C:2]1[C:3]([C:14]#[C:15][C:17]2[CH:24]=[CH:23][C:20]([C:21]#[N:22])=[CH:19][CH:18]=2)=[CH:4][C:5]2[C:6]([CH3:12])([CH3:13])[CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1

Participants

3

Reactant 2

HCID 12162Benzonitrile, 4-bromo-HCID 19786988HCID 19786988, compound

Product 1

HCID 19786992HCID 19786992, compound

Procedure

Using a process similar to that described in Example 1c, 4.4 g (22 millimoles) of (5,6,7,8-tetrahydro-3,8,8-trimethylnaphth-2-yl)-ethyne and 2.7 g (15 millimoles) of 4-bromobenzonitrile were converted to the title compound. 1.3 g (29%) of product of melting point 128°-130° C. were obtained after recrystallization from ethanol.

Sources & evidence

ORD record
ord-7198b93e7d28476fa86bfbf126133639
Source dataset
uspto-grants-1989_02
Patent number
US04806558

Reaction notes

Loading…