Potassium Carbonate → HCID 21272897, compound

HRID 1382663Notes

Reaction equation

HRID 1382663 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13](=[O:14])[C:12]([CH:15]([CH3:18])[CH2:16][CH3:17])=[C:11]([Cl:19])[NH:10]2)[CH:5]=[C:6]([Cl:8])[CH:7]=1.C(=O)([O-])[O-:21].[K+].[K+].ClC1C=CC=C(C(OO)=O)C=1>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13](=[O:14])[C:12]([OH:21])([CH:15]([CH3:18])[CH2:16][CH3:17])[C:11]([Cl:19])=[N:10]2)[CH:5]=[C:6]([Cl:8])[CH:7]=1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 70297m-Chloroperbenzoic acidHCID 21272889HCID 21272889, compound

Product 1

HCID 21272897HCID 21272897, compoundYield 46.3%

Procedure

0.7 g of 1-(3,5-dichlorophenyl)-3-chloro-4-(1-methylpropyl)-5-pyrazolone and 0.7 g of potassium carbonate were cooled to -20° C. and 0.7 g of 75% m-chloroperbenzoic acid were added all at once. The procedure of Example 46 was followed to obtain 0.34 g of 1-(3,5-dichlorophenyl)-3-chloro-4-hydroxy-4-(1-methylpropyl)-5-pyrazolone used as is for the next step.

Sources & evidence

ORD record
ord-62623be01ea14e438b12330cc053b1ce
Source dataset
uspto-grants-1989_02
Patent number
US04808210

Reaction notes

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