Hydrazine hydrate (1:1) → HCID 14350420, compound

HRID 1382868Notes

Reaction equation

HRID 1382868 reaction equation
Cl[C:2]1[C:11]2[C:10](=[O:12])[N:9]([CH3:13])[C:8](=[O:14])[N:7]([CH3:15])[C:6]=2[CH:5]=[CH:4][N:3]=1.O.[NH2:17][NH2:18]>CO>[NH:17]([C:2]1[C:11]2[C:10](=[O:12])[N:9]([CH3:13])[C:8](=[O:14])[N:7]([CH3:15])[C:6]=2[CH:5]=[CH:4][N:3]=1)[NH2:18]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 14350419HCID 14350419, compound

Product 1

HCID 14350420HCID 14350420, compoundYield 93.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

0.69 g of Compound 17 and 0.31 g of hydrazine hydrate were added to 20 ml of methanol and the solution was heated under reflux for 24 hr. The solvent was distilled off to give 0.63 g of 5-hydrazino-1,3-dimethylpyrido[4,3-d]pyrimidine-2,4-dione (Compound 18).

Workup

  1. temperaturethe solution was heated
  2. temperatureunder reflux for 24 hr
  3. distillationThe solvent was distilled off

Sources & evidence

ORD record
ord-76846167a09a425686e088a6cd863a18
Source dataset
uspto-grants-1989_02
Patent number
US04808618

Reaction notes

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