反应详情

To a warm (40° C.) solution of 2-sulfamoylfuro[3,2-c]pyridine (2.68 g, 13.5 mmol) in methanol (30 ml) and ethyl acetate (10 ml) was added dropwise a solution of m-chloroperbenzoic acid (3.22 g, 15 mmol) in ethyl acetate (13 ml). The reaction mixture was stirred for 18 hours as product precipitated. The pure product was collected by filtration and crystallized from hot dimethyl sulfoxide by dilution with ethanol to give 2.4 g (83% yield), m.p. 247°-248° C.

1. customprecipitated
2. filtrationThe pure product was collected by filtration
3. customcrystallized from hot dimethyl sulfoxide by dilution with ethanol
4. customto give 2.4 g (83% yield), m.p. 247°-248° C.