Hydrochloric Acid → N-(3-chloro-4-fluorophenyl)-7-(cyclopropylmethoxy)-6-nitroquinazolin-4-amine
Reaction equation
[CH3:36][N:37]([CH3:38])[CH:39]=[O:40].[CH3:6][C:7]([CH3:8])([O-:9])[CH3:10].[CH:1]1([CH2:4][OH:5])[CH2:2][CH2:3]1.[Cl:12][c:13]1[cH:14][c:15]([NH:20][c:21]2[n:22][cH:23][n:24][c:25]3[cH:26][c:27]([F:34])[c:28]([N+:31](=[O:32])[O-:33])[cH:29][c:30]23)[cH:16][cH:17][c:18]1[F:19].[ClH:35].[K+:11].[OH2:41]>>[CH:1]1([CH2:4][O:5][c:27]2[cH:26][c:25]3[n:24][cH:23][n:22][c:21]([NH:20][c:15]4[cH:14][c:13]([Cl:12])[c:18]([F:19])[cH:17][cH:16]4)[c:30]3[cH:29][c:28]2[N+:31](=[O:32])[O-:33])[CH2:2][CH2:3]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-bde3771b368a4ac9b1c1312aaa7ea63d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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