HCID 54385380, compound → HCID 21042177, compound

HRID 1383284Notes

Reaction equation

HRID 1383284 reaction equation
[CH3:1][C:2]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][O:8][C:7](=[O:18])[CH2:6][CH2:5][CH2:4][CH:3]=1.[H][H]>C(OCC)(=O)C.[Pd]>[CH3:1][CH:2]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][O:8][C:7](=[O:18])[CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

5

Reactant 2

HCID 54385380HCID 54385380, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21042177HCID 21042177, compoundYield 92.9%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

28 g (0.11 mol) of 7-methyloxacyclohexadec-6-en-2-one were dissolved in 200 ml of ethyl acetate and hydrogenated in the presence of 2 g of 5% palladium-on-carbon under 150 mbar of hydrogen. The mixture was filtered over Celite, concentrated and distilled in a bulb-tube. 26 g (92%) of 7-methyloxacyclohexadecan-2-one were obtained having the following characteristics:

Workup

  1. filtrationThe mixture was filtered over Celite
  2. concentrationconcentrated
  3. distillationdistilled in a bulb-tube

Sources & evidence

ORD record
ord-d10a067371394e8ab533a2cbe5eed4d6
Source dataset
uspto-grants-2001_07
Patent number
US06255276B1

Reaction notes

Loading…