Hydrazine hydrate (1:1) → HCID 10921895, compound

HRID 1383394Notes

Reaction equation

HRID 1383394 reaction equation
[NH2:1][C:2]1[C:11]([Cl:12])=[CH:10][C:5]([C:6](OC)=[O:7])=[C:4]([O:13][CH3:14])[CH:3]=1.O.[NH2:16][NH2:17]>C(O)C>[NH2:1][C:2]1[C:11]([Cl:12])=[CH:10][C:5]([C:6]([NH:16][NH2:17])=[O:7])=[C:4]([O:13][CH3:14])[CH:3]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 700493Methyl 4-amino-5-chloro-2-methoxybenzoate

Product 1

HCID 10921895HCID 10921895, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

51.5 g (0.239 mol) of methyl 4-amino-5-chloro-2-methoxybenzoate suspended in 460 ml of ethanol are introduced into a 1 l reactor. 119 g (2.39 mol) of hydrazine hydrate are added, over 15 min, and the mixture is refluxed for 15 h.

Workup

  1. additionare introduced into a 1 l reactor
  2. temperaturethe mixture is refluxed for 15 h.

Sources & evidence

ORD record
ord-d96cd2a7b11d477ca1a86d318fafecef
Source dataset
uspto-grants-2001_07
Patent number
US06255319B1

Reaction notes

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