Diphosgene → HCID 10199250, compound

HRID 1383433Notes

Reaction equation

HRID 1383433 reaction equation
Cl[C:2]([O:5]C(Cl)=O)(Cl)Cl.CO[N:11]([C:24](=[O:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[N:12]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:13]([O:15]CC)=O>O1CCCC1>[CH3:2][O:5][C:30]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[C:24]1[O:31][C:13](=[O:15])[N:12]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[N:11]=1

Participants

4

Reactant 2

HCID 10426DiphosgeneHCID 86757108HCID 86757108, compound

Product 1

HCID 10199250HCID 10199250, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

3,2 ml of trichloromethylchloroformate (diphosgene) are added, with stirring, to a solution of 6,3 g of ethyl N′-methoxybenzoyl-N-phenyl-hydrazine-carboxylate in anhydrous tetrahydrofuran at ambient temperature. After one hour's stirring at ambient temperature the solvent is distilled off in vacuo and the residue remaining is recrystallised from ethanol. Yield: 6.5 g (96%), melting point: 112-115° C.

Workup

  1. distillationis distilled off in vacuo
  2. customthe residue remaining is recrystallised from ethanol

Sources & evidence

ORD record
ord-6aa03d849262480b9fbc0eb1166fd49d
Source dataset
uspto-grants-2001_07
Patent number
US06255327B1

Reaction notes

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