Diisopropylamine → 2-[4-(5-Bromopyridin-2-ylethynyl)-2-methylphenoxy]ethanol

HRID 138440Notes

Reaction equation

HRID 138440 reaction equation
[Br:14][c:15]1[n:16][cH:17][c:18]([Br:21])[cH:19][cH:20]1.[C:1](#[CH:2])[c:3]1[cH:4][c:5]([CH3:13])[c:6]([O:7][CH2:8][CH2:9][OH:10])[cH:11][cH:12]1.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH:22]([NH:23][CH:24]([CH3:25])[CH3:26])([CH3:27])[CH3:28].[Cu:34][I:35]>>[C:1](#[C:2][c:15]1[n:16][cH:17][c:18]([Br:21])[cH:19][cH:20]1)[c:3]1[cH:4][c:5]([CH3:13])[c:6]([O:7][CH2:8][CH2:9][OH:10])[cH:11][cH:12]1

Participants

6

Reactant 5

HCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 693532,5-DibromopyridineHCID 575658612-(4-Ethynyl-2-methylphenoxy)ethanol

Product 1

HCID 690586072-[4-(5-Bromopyridin-2-ylethynyl)-2-methylphenoxy]ethanol

Sources & evidence

ORD record
ord-ea81849cacce43d6a4d69b231dad8528
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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