反应详情

温度

77.5 °C

A mixture of phenylhydrazine (4.29 g) and fumaronitrile (3.1 g), where the phenylhydrazine served as a solvent, was heated at 75-80° C. for 20 hours. Purification by flash chromatography on silica gel and crystallization from dichloromethane/hexane gave the title compound (3.29 g, 45%), m.p. 97-98° C.

1. customPurification by flash chromatography
2. customon silica gel and crystallization from dichloromethane/hexane