反应详情

2.5 g of 8-cyclopropyl-2-methyleneoctanoic acid ethyl ester, in the form of a yellowish oil, which is purified by chromatography on silica gel (migrating agent: 90:10 petroleum ether/ethyl acetate), are obtained by the procedure described in Example (1b) from 4.53 g of (6-cyclopropylhexyl)-malonic acid ethyl ester 0.64 g of paraformaldehyde, 4 ml of pyridine and 0.2 ml of piperidine.

1. custom2.5 g of 8-cyclopropyl-2-methyleneoctanoic acid ethyl ester, in the form of a yellowish oil, which is purified by chromatography on silica gel (migrating agent: 90:10 petroleum ether/ethyl acetate)
2. customare obtained by the procedure