反应详情

Boiling stones and 42 gm (0.12 mol) of 2-(N-tert. butyl)sulfamoyl-5-methyl-furan-3-carboxylic acid were heated in a round bottom flask for 2 hours at 150° C. The cooled reaction mixture was taken up in 1 liter of ethyl acetate. After refluxing the solution was treated with activated charcoal, filtered and evaporated. 22.8 gm (69% of theory) of crystalline 5-methyl-2-sulfamoyl-furan-3-carboxylic acid were obtained.

1. customThe cooled reaction mixture
2. temperatureAfter refluxing the solution
3. filtrationfiltered
4. customevaporated