Sodium ion → Methyl 2-[1-(3-chloro-2-pyridinyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-3-(1-methoxypropan-2-yloxy)propanoate

HRID 138905Notes

Reaction equation

HRID 138905 reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl:16][c:17]1[c:18]2[c:19]([n:20][cH:21][n:22]1)[n:23](-[c:26]1[n:27][cH:28][cH:29][cH:30][c:31]1[Cl:32])[n:24][cH:25]2.[H-:1].[Na+:2].[OH:3][CH:4]([C:5](=[O:6])[O:7][CH3:8])[CH2:9][O:10][CH:11]([CH2:12][O:13][CH3:14])[CH3:15]>>[O:3]([CH:4]([C:5](=[O:6])[O:7][CH3:8])[CH2:9][O:10][CH:11]([CH2:12][O:13][CH3:14])[CH3:15])[c:17]1[c:18]2[c:19]([n:20][cH:21][n:22]1)[n:23](-[c:26]1[n:27][cH:28][cH:29][cH:30][c:31]1[Cl:32])[n:24][cH:25]2

Participants

7

Reactant 6

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 166653HydrideHCID 575044824-Chloro-1-(3-chloropyridin-2-YL)-1H-pyrazolo[3,4-D]pyrimidineHCID 76545418Methyl 2-hydroxy-3-(1-methoxypropan-2-yloxy)propanoate

Product 1

HCID 76550472Methyl 2-[1-(3-chloro-2-pyridinyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-3-(1-methoxypropan-2-yloxy)propanoate

Sources & evidence

ORD record
ord-5732dc8f650c461d88457b182dd44d05
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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