Potassium Carbonate → HCID 23467865, compound

HRID 1389137Notes

Reaction equation

HRID 1389137 reaction equation
[CH2:1]([O:3][C:4]1[C:9]2[O:10][CH:11]3[CH2:20][CH2:19][CH2:18][CH:17]4[C:12]3([CH2:13][CH2:14][NH:15][CH2:16]4)[C:8]=2[CH:7]=[CH:6][CH:5]=1)[CH3:2].[CH:21]1([CH2:27]Br)[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[CH:21]1([CH2:27][N:15]2[CH2:14][CH2:13][C:12]34[C:8]5[CH:7]=[CH:6][CH:5]=[C:4]([O:3][CH2:1][CH3:2])[C:9]=5[O:10][CH:11]3[CH2:20][CH2:19][CH2:18][CH:17]4[CH2:16]2)[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 137636Cyclohexane, (bromomethyl)-HCID 23467864HCID 23467864, compound

Product 1

HCID 23467865HCID 23467865, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Treating 9-ethoxy-2,3,4,4a,5,6,7,7a-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinoline with cyclohexylmethyl bromide in the presence of a base such as potassium carbonate in a solvent such as dimethylformamide gives 3-cyclohexylmethyl-9-ethoxy-2,3,4,4a,5,6,7,7a-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinoline ##STR77##

Sources & evidence

ORD record
ord-5646dec750844e369d32cb1a671a6582
Source dataset
uspto-grants-1981_01
Patent number
US04243668

Reaction notes

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