Ethanol → HCID 20297261, compound

HRID 1389617Notes

Reaction equation

HRID 1389617 reaction equation
[O:1]([C:8]1[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=1)[CH:11]=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:16]1([SH:22])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.C(Cl)(Cl)Cl.[OH-:27].[K+].[CH2:29]([OH:31])C>>[C:16]1([S:22][CH:11]([C:10]2[CH:13]=[CH:14][CH:15]=[C:8]([O:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[CH:9]=2)[C:29]([OH:31])=[O:27])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

6

Reactant 5

HCID 702Ethanol2×HCID 6212ChloroformHCID 7969ThiophenolHCID 14797Potassium HydroxideHCID 382843-Phenoxybenzaldehyde

Product 1

HCID 20297261HCID 20297261, compoundYield 65%

Procedure

1.10 g of 3-phenoxybenzaldehyde, 1.65 g of thiophenol and 1.8 g of chloroform were dissolved in 5 ml of ethanol, and to the resulting solution was added dropwise a solution of 2.0 g of potassium hydroxide in 10 ml of ethanol over a period of 90 minutes. The reaction mixture was then stirred overnight at room temperature and then worked up in the same manner as described in Example 1 to obtain 1.10 g (65% yield) of 2-phenylthio-2-(3-phenoxyphenyl)acetic acid.

Sources & evidence

ORD record
ord-94cc084482774713b81d526f633a1324
Source dataset
uspto-grants-1981_01
Patent number
US04245108

Reaction notes

Loading…