1,2-Dichloroethane → 4-((6-Bromopyridin-2-yl)methyl)morpholine

HRID 138962Notes

Reaction equation

HRID 138962 reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH:8]=[O:9])[n:7]1.[C:16]([O:17][BH-:18]([O:19][C:20](=[O:21])[CH3:22])[O:23][C:24](=[O:25])[CH3:26])(=[O:27])[CH3:28].[C:40](=[O:41])([OH:42])[O-:43].[CH2:10]1[CH2:11][O:12][CH2:13][CH2:14][NH:15]1.[CH3:34][CH2:35][O:36][C:37](=[O:38])[CH3:39].[Cl:30][CH2:31][CH2:32][Cl:33].[Na+:29].[Na+:44].[Na+:45].[Na+:46].[O-:47][C:48](=[O:49])[O-:50]>>[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH2:8][N:15]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[n:7]1

Participants

9

Reactant 8

HCID 111,2-DichloroethaneHCID 769Bicarbonate IonHCID 923Sodium ion4×HCID 8083MorpholineHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 2724942TriacetoxyborohydrideHCID 27570096-Bromopyridine-2-carbaldehyde

Product 1

HCID 234381474-((6-Bromopyridin-2-yl)methyl)morpholine

Sources & evidence

ORD record
ord-81cfb71aa8bf4902b1893d759dfddcc8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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