Dimethylformamide → HCID 20294268, compound

HRID 1389964Notes

Reaction equation

HRID 1389964 reaction equation
[CH2:1]([O:3][C:4]1[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH3:19])=[CH:13][C:5]=1[N:6]([CH2:10][CH2:11][CH3:12])[CH2:7][CH2:8][CH3:9])[CH3:2].P(Cl)(Cl)(Cl)=O.CN(C)[CH:27]=[O:28]>>[CH2:1]([O:3][C:4]1[CH:16]=[C:15]([CH:27]=[O:28])[C:14]([O:17][CH2:18][CH3:19])=[CH:13][C:5]=1[N:6]([CH2:7][CH2:8][CH3:9])[CH2:10][CH2:11][CH3:12])[CH3:2]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 20294269HCID 20294269, compound

Product 1

HCID 20294268HCID 20294268, compound

Procedure

2,5-Diethoxy-4-formyl-N,N-di-n-propylaniline was prepared in situ by taking 2,5-diethoxy-N,N-di-n-propylaniline (2.65 g., 0.01 mole) in a mixture of N,N-dimethylformamide (10 ml.) and phosphorus oxychloride (1.68 g., 0.011 mole) and heating on a steam bath for two hours. The mixture was then poured into ice water to give the coupling solution.

Workup

  1. temperatureheating on a steam bath for two hours
  2. customto give the coupling solution

Sources & evidence

ORD record
ord-89cf360d67c74701a5260c80a2eb7df0
Source dataset
uspto-grants-1981_01
Patent number
US04247458

Reaction notes

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