Propane sultone → HCID 86737462, compound

HRID 1390087Notes

Reaction equation

HRID 1390087 reaction equation
[Na:1].[SH:2][C:3]1[CH:9]=[C:8]([N+:10]([O-:12])=[O:11])[CH:7]=[CH:6][C:4]=1[NH2:5].[CH2:13]1[S:17](=[O:19])(=[O:18])[O:16][CH2:15][CH2:14]1>C(O)C>[Na:1].[S:17]([CH2:13][CH2:14][CH2:15][S:2][C:3]1[CH:9]=[C:8]([N+:10]([O-:12])=[O:11])[CH:7]=[CH:6][C:4]=1[NH2:5])([OH:19])(=[O:18])=[O:16]

Participants

5

Reactant 3

HCID 14264Propane sultoneHCID 5360545SodiumHCID 109866912-Amino-5-nitrobenzenethiol

Product 1

HCID 86737462HCID 86737462, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a mixture of 50 ml. of ethanol and 0.46 g. of metallic sodium were dissolved 3.4 g. of 2-mercapto-4-nitroaniline and 2.44 g. of propanesultone were added thereto under stirring. Thereafter, heating was conducted at 40°-50° C. for 1 hour and the crystalline substance thus separated was recovered by filtration, washed with ethanol and acetone and then dried to give 2 g. of the desired product. m.p. 181°-193° C.

Workup

  1. additionIn a mixture of 50 ml
  2. temperatureThereafter, heating
  3. customthe crystalline substance thus separated
  4. filtrationwas recovered by filtration
  5. washwashed with ethanol and acetone
  6. customdried
  7. customto give 2 g

Sources & evidence

ORD record
ord-7f200ea02ab04d0e953f0c0d1e0b7c88
Source dataset
uspto-grants-1981_01
Patent number
US04247629

Reaction notes

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