反应详情

Ethyl 6,6-dichloro-3-ethyl-7-oxo-1-aza-4-oxabicyclo[3.2.0]heptane-2-carboxylate (e21) (25mg, 0.089 m.mole) in EtOH/H2O containing 2 equivalents of NaHCO3 was hydrogenated over Pd/CaCO3 for 45 minutes, extracted into ethyl acetate, dried and evaporated under reduced pressure. Chromatography yielded the title compound (e22) (9 mg, 41%) M+ 247.0612 C10H14ClNO4 requires 247.0611

1. extractionextracted into ethyl acetate
2. customdried
3. customevaporated under reduced pressure