4-Nitrobenzyl chloride → HCID 21331815, compound

HRID 1390995Notes

Reaction equation

HRID 1390995 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8]Cl)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.Cl.[Br:14][C:15]1[CH:20]=[CH:19][C:18]([N:21]2[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]2)=[CH:17][CH:16]=1>C(N(CC)CC)C>[Br:14][C:15]1[CH:16]=[CH:17][C:18]([N:21]2[CH2:26][CH2:25][N:24]([CH2:8][C:7]3[CH:10]=[CH:11][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=3)[CH2:23][CH2:22]2)=[CH:19][CH:20]=1

Participants

4

Reactant 2

HCID 74824-Nitrobenzyl chlorideHCID 19817077HCID 19817077, compound

Product 1

HCID 21331815HCID 21331815, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In the manner given in Example 1A, p-nitrobenzyl chloride is reacted with 1-(4-bromophenyl)piperazine dihydrochloride in the presence of triethylamine to give 1-(4-bromophenyl)-4-(p-nitrobenzyl)piperazine

Sources & evidence

ORD record
ord-3e2b370a1bef4b94af871e31527c1159
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

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