4-Nitrobenzyl chloride → HCID 21331827, compound

HRID 1390998Notes

Reaction equation

HRID 1390998 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8]Cl)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.Cl.[CH2:14]([O:17][C:18]1[CH:19]=[C:20]([N:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)[CH:21]=[C:22]([O:24][CH2:25][CH2:26][CH3:27])[CH:23]=1)[CH2:15][CH3:16]>C(N(CC)CC)C>[CH2:14]([O:17][C:18]1[CH:19]=[C:20]([N:28]2[CH2:29][CH2:30][N:31]([CH2:8][C:7]3[CH:10]=[CH:11][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=3)[CH2:32][CH2:33]2)[CH:21]=[C:22]([O:24][CH2:25][CH2:26][CH3:27])[CH:23]=1)[CH2:15][CH3:16]

Participants

4

Reactant 2

HCID 74824-Nitrobenzyl chlorideHCID 21331841HCID 21331841, compound

Product 1

HCID 21331827HCID 21331827, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In the manner given in Example 1A, p-nitrobenzyl chloride is reacted with 1-(3,5-dipropoxyphenyl)piperazine dihydrochloride in the presence of triethylamine to give 1-(3,5-dipropoxyphenyl) 4-(p-nitrobenzyl)piperazine.

Sources & evidence

ORD record
ord-04f3955719f1455786074b6ae0c9d7b8
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

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