4-Nitrobenzyl chloride → HCID 21331804, compound

HRID 1391003Notes

Reaction equation

HRID 1391003 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8]Cl)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.Cl.[CH2:14]([C:16]1[C:21]([CH2:22][CH3:23])=[CH:20][CH:19]=[CH:18][C:17]=1[N:24]1[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1)[CH3:15]>C(N(CC)CC)C>[CH2:14]([C:16]1[C:21]([CH2:22][CH3:23])=[CH:20][CH:19]=[CH:18][C:17]=1[N:24]1[CH2:29][CH2:28][N:27]([CH2:8][C:7]2[CH:10]=[CH:11][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)[CH2:26][CH2:25]1)[CH3:15]

Participants

4

Reactant 2

HCID 74824-Nitrobenzyl chlorideHCID 21331873HCID 21331873, compound

Product 1

HCID 21331804HCID 21331804, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In the manner given in Example 1A, p-nitrobenzyl chloride is reacted with (2,3-diethylphenyl)piperazine dihydrochloride in the presence of triethylamine to give 1-(2,3-diethylphenyl)-4-(p-nitrobenzyl)piperazine.

Sources & evidence

ORD record
ord-6b5a8c395a154b60914b55cc1037fdf3
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

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