1-chloro-4-(methoxymethyl)benzene → 4-Chlorobenzaldehyde

HRID 1392570Notes

Reaction equation

HRID 1392570 reaction equation
C[O:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([Cl:10])=[CH:6][CH:5]=1.Br([O-])(=O)=O.[Na+]>>[Cl:10][C:7]1[CH:8]=[CH:9][C:4]([CH:3]=[O:2])=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 119839551-chloro-4-(methoxymethyl)benzeneHCID 23668195Sodium Bromate

Product 1

HCID 77264-Chlorobenzaldehyde

Procedure

In the same manner as in Example 3, the operation was conducted, except that 0.63 g (4 mmols) of p-chlorobenzyl methyl ether was used in place of m-methoxybenzyl alcohol and also 0.2 g (1.35 mmols) of sodium bromate was used. With respect to the components in the reaction solution, the intended p-chlorobenzaldehyde was produced in an area ratio, as determined by gas chromatography, of 91.0%.

Sources & evidence

ORD record
ord-ed53b7f4aecc46c0ae8e15917403dc14
Source dataset
uspto-grants-2008_03
Patent number
US07342138B2

Reaction notes

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