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HRID1394684

反应详情

EQUATION

反应方程式

HRID 1394684 的结构方程式

REACTANTS

反应物

2
结构：O=P(Cl)(Cl)Cl
HCID24813

Phosphoric trichloride

Cl3OP

结构：Cc1cc(-c2oc(C)c(C)[n+]2[O-])ccc1F
HCID22273855

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(-c2nc(CCl)c(C)o2)ccc1F
HCID21974259

4-(Chloromethyl)-2-(4-fluoro-3-methylphenyl)-5-methyloxazole

C12H11ClFNO

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClC(Cl)Cl
溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

In analogy to the procedure described in example 2 b], 2-(4-fluoro-3-methyl-phenyl)-4,5-dimethyl-oxazole 3-oxide was treated with phosphorous oxychloride in chloroform to yield 4-chloromethyl-2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazole as colorless solid.