1-Pyrrolidineethanamine → [3-(2-methylsulfanyl-pyrimidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-(2-pyrrolidin-1-yl-ethyl)-amine

HRID 139469Notes

Reaction equation

HRID 139469 reaction equation
[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[CH3:34][CH:35]([OH:36])[CH3:37].[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:7]1)[nH:8][n:9][c:10]2-[c:11]1[n:12][c:13]([S:17][CH3:18])[n:14][cH:15][cH:16]1.[N:19]1([CH2:24][CH2:25][NH2:26])[CH2:20][CH2:21][CH2:22][CH2:23]1>>[c:2]1([NH:26][CH2:25][CH2:24][N:19]2[CH2:20][CH2:21][CH2:22][CH2:23]2)[n:3][cH:4][c:5]2[c:6]([n:7]1)[nH:8][n:9][c:10]2-[c:11]1[n:12][c:13]([S:17][CH3:18])[n:14][cH:15][cH:16]1

Participants

5

Reactant 4

HCID 13441-PyrrolidineethanamineHCID 3776IsopropanolHCID 8471TriethylamineHCID 178503430HCID 178503430, compound

Product 1

HCID 178503434[3-(2-methylsulfanyl-pyrimidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-(2-pyrrolidin-1-yl-ethyl)-amine

Sources & evidence

ORD record
ord-d982a89a2fb54803ae611dc8049dd2df
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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