Hydrochloric Acid → HCID 20340251, compound

HRID 1395128Notes

Reaction equation

HRID 1395128 reaction equation
C([O:3][C:4](=[O:22])[CH2:5][CH2:6][CH2:7][S:8][C:9](=[S:21])[NH:10][CH2:11][CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=1)C.Cl>C(O)(=O)C>[Cl:20][C:17]1[CH:16]=[CH:15][C:14]([CH2:13][CH2:12][CH2:11][NH:10][C:9]([S:8][CH2:7][CH2:6][CH2:5][C:4]([OH:22])=[O:3])=[S:21])=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54379090HCID 54379090, compound

Product 1

HCID 20340251HCID 20340251, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

10 G. of 4-{[[3-(p-chlorophenyl)propyl]thiocarbamoyl]-thio}-butyric acid ethyl ester dissolved in 100 ml. of acetic acid were stirred under slight reflux for 8 hours with 50 ml. of half-concentrated hydrochloric acid. The mixture was evaporated in vacuo, the residue recrystallized from carbon tetrachloride, and 4.4 g. of 4-{[[(p-chlorophenyl)propyl]-thiocarbamoyl]thio}-butyric acid having a melting point of 98°-100° C. were obtained.

Workup

  1. temperatureunder slight reflux for 8 hours with 50 ml
  2. customThe mixture was evaporated in vacuo
  3. customthe residue recrystallized from carbon tetrachloride, and 4.4 g

Sources & evidence

ORD record
ord-d54e4b9b374245468409b25b1f3fcfcd
Source dataset
uspto-grants-1980_05
Patent number
US04202832

Reaction notes

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