Diglyme → HCID 178448844, compound

HRID 1395232Notes

Reaction equation

HRID 1395232 reaction equation
[CH2:1]([NH:5][C:6]1[C:11]2[CH:12]=[N:13][C:14]3[N:18](CC4OC=CC=4)[N:17]=[CH:16][C:15]=3[C:10]=2[N:9]2[N:25]=[C:26]([CH3:28])[CH:27]=[C:8]2[N:7]=1)[CH2:2][CH2:3][CH3:4].COCCOCCOC.[Se](=O)=O>>[CH2:1]([NH:5][C:6]1[C:11]2[CH:12]=[N:13][C:14]3[NH:18][N:17]=[CH:16][C:15]=3[C:10]=2[N:9]2[N:25]=[C:26]([CH3:28])[CH:27]=[C:8]2[N:7]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 3

HCID 8150DiglymeHCID 24007Selenium DioxideHCID 23331612HCID 23331612, compound

Product 1

HCID 178448844HCID 178448844, compound

Procedure

0.01 mol of N-butyl-8-furfuryl-2-methyl-8H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidin-5-amine is heated in 50 ml of diethyleneglycol dimethyl ether containing 0.01 mol of selenium dioxide at reflux temperature with stirring for two hours. The mixture is filtered hot and evaporated to dryness. N-butyl-2-methyl-8H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidin-5-amine remains.

Workup

  1. temperatureat reflux temperature
  2. filtrationThe mixture is filtered hot
  3. customevaporated to dryness

Sources & evidence

ORD record
ord-0fe73ad70e2046bfabe644c03e8225af
Source dataset
uspto-grants-1980_05
Patent number
US04202899

Reaction notes

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