Dimethyl N-cyanodithioiminocarbonate → HCID 136018057, compound

HRID 1395385Notes

Reaction equation

HRID 1395385 reaction equation
[C:1]([N:3]=[C:4](SC)SC)#[N:2].[CH2:9]([N:11]([CH2:13][C:14]1[O:18][C:17]([CH2:19][S:20][CH2:21][CH2:22][NH2:23])=[CH:16][CH:15]=1)[CH3:12])[CH3:10].CNC(=N)S.[CH2:29]([NH2:32])[C:30]#[CH:31]>C(O)(C)C>[C:1]([NH:3][C:4]([NH:32][CH2:29][C:30]#[CH:31])=[N:23][CH2:22][CH2:21][S:20][CH2:19][C:17]1[O:18][C:14]([CH2:13][N:11]([CH2:9][CH3:10])[CH3:12])=[CH:15][CH:16]=1)#[N:2]

Participants

6

Reactant 4

HCID 66289Dimethyl N-cyanodithioiminocarbonateHCID 239041PropargylamineHCID 20339244HCID 20339244, compoundHCID 178485201HCID 178485201, compound

Product 1

HCID 136018057HCID 136018057, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

When an isopropyl alcohol solution of dimethyl cyanodithioimidocarbonate [prepared according to the procedure described in J. Org. Chem., 32, 1566 (1967)] is reacted with 2-[(5-{[N-ethyl-N-methylamino]methyl}-2-furyl)methylthio]ethylamine and the resultant N-cyano-N'-2-[(5-{[N-ethyl-N-methylamino]methyl}-2-furyl)methylthio]-ethyl}-S-methylisothiourea treated with propargylamine in the procedure of Example 2, there is produced N-cyano-N'-(2-propyn-1-yl)-N"-{2-[(5-{[N-ethyl-N-methylamino]methyl}-2-furyl)methylthio]ethyl}guanidine.

Sources & evidence

ORD record
ord-7dd00d074e3e4d749724dec868bfca97
Source dataset
uspto-grants-1980_05
Patent number
US04203909

Reaction notes

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