反应详情

When an isopropyl alcohol solution of dimethyl cyanodithioimidocarbonate [prepared according to the procedure described in J. Org. Chem., 32, 1566 (1967)] is reacted with 2-[(5-{[N-ethyl-N-methylamino]methyl}-2-furyl)methylthio]ethylamine and the resultant N-cyano-N'-2-[(5-{[N-ethyl-N-methylamino]methyl}-2-furyl)methylthio]-ethyl}-S-methylisothiourea treated with propargylamine in the procedure of Example 2, there is produced N-cyano-N'-(2-propyn-1-yl)-N"-{2-[(5-{[N-ethyl-N-methylamino]methyl}-2-furyl)methylthio]ethyl}guanidine.