反应详情

A mixture of 3-dimethylaminopropanol (10.3 g), N,N1 -dimethylthiourea (10.4 g) and aqueous hydrobromic acid (48%, 60 ml) was boiled under reflux for 18 hours and evaporated to dryness. The residue was recrystallised from ethanol to give the dihydrobromide of the title compound m.p. 173°-174°. (Found: C, 27.4; H, 6.0; N, 12.0; S, 9.1; Br, 45.3; C8H19N3S.2HBr, requires: C, 27.4; H, 6.0; N, 12.0; S, 9.1; Br. 45.5%.)

1. temperatureunder reflux for 18 hours
2. customevaporated to dryness
3. customThe residue was recrystallised from ethanol