Methyl Bromide → HCID 70596338, compound

HRID 1395659Notes

Reaction equation

HRID 1395659 reaction equation
[C:1]1([C:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:8]2[CH:16]3[N:11]([CH2:12][CH2:13][CH2:14][CH2:15]3)[CH2:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:23][Br:24]>CC(C)=O>[CH3:23][Br:24].[C:1]1([C:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:8]2[CH:16]3[N:11]([CH2:12][CH2:13][CH2:14][CH2:15]3)[CH2:10][CH2:9]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 6323Methyl BromideHCID 12876530HCID 12876530, compound

Product 1

HCID 70596338HCID 70596338, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

In 10 ml. of acetone was dissolved 0.5 g. of 1-diphenylmethyleneindolizidine. To the resulting solution was added 2 ml. of methyl bromide. The mixture was allowed to stand for 30 mins. The crystals obtained after distilling of the solvent were washed with acetone to obtain 540 mg. of colorless plate-like crystals showing a melting point of 210°-211° C. were obtained.

Workup

  1. additionTo the resulting solution was added 2 ml
  2. customThe crystals obtained
  3. distillationafter distilling of the solvent
  4. washwere washed with acetone
  5. customto obtain 540 mg
  6. customwere obtained

Sources & evidence

ORD record
ord-b860a80120be4c32ae473d86a13deee5
Source dataset
uspto-grants-1980_05
Patent number
US04205074

Reaction notes

Loading…