反应详情

650 mg of tetrahydro-4H-pyran-4-one together with 950 mg of morpholine were dissolved in 10 ml of toluene and the mixture was heated under reflux in a light water separator for 5 hours. Subsequently, the mixture was concentrated under reduced pressure, and residue (1.3 g) was used further without further workup.

1. temperaturethe mixture was heated
2. concentrationSubsequently, the mixture was concentrated under reduced pressure, and residue (1.3 g)