反应详情

The mixture of 4-bromobenzene-1,2-diamine (200 mg, 1.1 mmol), CDI (174 mg, 1.1 mmol) in dioxane was reacted at 50° C. for 16 hours. The mixture was concentrated and the residue was dissolved in DCM and extracted with water with the combined organic phases dried by Na2SO4 and concentrated to give 300 mg of crude product which was used without further purification. LCMS (m/z): 213.1/214.1 [M+H]+/[M+2H]+

1. customwas reacted at 50° C. for 16 hours
2. concentrationThe mixture was concentrated
3. dissolutionthe residue was dissolved in DCM
4. extractionextracted with water with the combined organic phases
5. dry with materialdried by Na2SO4
6. concentrationconcentrated