Chloride → 1-Chloro-4-(4-fluorobenzyl)-5,6,7,8-tetrahydrophthalazine

HRID 140056Notes

Reaction equation

HRID 140056 reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[Cl-:13].[Cl:1][c:2]1[n:3][n:4][c:5]([Cl:12])[c:6]2[c:11]1[CH2:10][CH2:9][CH2:8][CH2:7]2.[F:14][c:15]1[cH:16][cH:17][c:18]([CH2:19][Zn+:20])[cH:21][cH:22]1>>[c:2]1([CH2:19][c:18]2[cH:17][cH:16][c:15]([F:14])[cH:22][cH:21]2)[n:3][n:4][c:5]([Cl:12])[c:6]2[c:11]1[CH2:10][CH2:9][CH2:8][CH2:7]2

Participants

5

Reactant 4

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 126224401,4-Dichloro-5,6,7,8-tetrahydrophthalazineHCID 178505762HCID 178505762, compound

Product 1

HCID 574716251-Chloro-4-(4-fluorobenzyl)-5,6,7,8-tetrahydrophthalazine

Sources & evidence

ORD record
ord-23b3b17381f647b5ac06e926e31a54d8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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