HRID1401845

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID14798

Sodium Hydroxide

HNaO

HCID78491

1-Butanol, 4-bromo-, 1-acetate

C6H11BrO2

结构：CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCNCC4)n3)ccc21

HCID53311543

未命名化合物

PRODUCTS

生成物

结构：CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCN(CCCCO)CC4)n3)ccc21

HCID67323438

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

The preparation is carried out as already described starting from 79 mg (0.214 mmol) of 1-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepane and 47 μl (0.321 mmol) of 4-bromobutyl acetate. The protecting group is cleaved off by means of a 1N NaOH solution in methanol. The product is in the form of the hydrochloride.