HRID1401869

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CC(C)(C)OC(=O)N1CCOC(C(=O)Nc2cccc(-c3ccc4c(c3)C(C)(C)CCC4(C)C)n2)C1

HCID67323275

未命名化合物

PRODUCTS

生成物

结构：CC1(C)CCC(C)(C)c2cc(-c3cccc(NC(=O)C4CNCCO4)n3)ccc21

HCID67249005

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

The protecting group is cleaved off as already described using TFA in DCM starting from 92 mg (0.19 mmol) of 2-[6-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)pyridin-2-ylcarbamoyl]morpholine-4-carboxylic acid tert-butyl ester from step b. The product is purified by means of preparative HPLC and is in the form of the TFA salt.

WORKUP

后处理

customThe product is purified by means of preparative HPLC