Dimethylacetamide → HCID 59129306, compound

HRID 1403970Notes

Reaction equation

HRID 1403970 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[C:5]([N+:12]([O-:14])=[O:13])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].C[C:19]([N:21]([CH3:23])[CH3:22])=O>CN(C=O)C>[N+:15]([C:3]1[CH:4]=[C:5]([N+:12]([O-:14])=[O:13])[C:6]([C:8]([F:10])([F:11])[F:9])=[CH:7][C:2]=1/[CH:1]=[CH:19]/[N:21]([CH3:23])[CH3:22])([O-:17])=[O:16]

Participants

4

Reactant 2

HCID 31374DimethylacetamideHCID 59129455HCID 59129455, compound

Product 1

HCID 59129306HCID 59129306, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of 1-methyl-2,4-dinitro-5-trifluoromethyl-benzene (2.0 g, 8.0 mmol) and DMA (1.0 g, 8.2 mmol) in DMF (20 mL) was stirred at 100° C. for 30 min. The mixture was poured into ice-water and stirred for 1 h. The precipitate was filtered and washed with water to give (E)-2-(2,4-dinitro-5-(trifluoromethyl)phenyl)-N,N-dimethylethenamine (2.1 g, 86%).

Workup

  1. stirringstirred for 1 h
  2. filtrationThe precipitate was filtered
  3. washwashed with water

Sources & evidence

ORD record
ord-323ba545cb5e4d5dbe95938da74ed11d
Source dataset
uspto-grants-2014_12
Patent number
US08912199B2

Reaction notes

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