Hydrochloric Acid → HCID 45089373, compound

HRID 1406471Notes

Reaction equation

HRID 1406471 reaction equation
C([NH:4][C:5]1[CH:13]=[CH:12][C:8]([C:9]([OH:11])=[O:10])=[C:7](C)[C:6]=1[N+:15]([O-:17])=[O:16])(=O)C.Cl.O1CCOC[CH2:20]1>>[NH2:4][C:5]1[C:6]([N+:15]([O-:17])=[O:16])=[CH:7][C:8]([C:9]([OH:11])=[O:10])=[C:12]([CH3:20])[CH:13]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 69594216HCID 69594216, compound

Product 1

HCID 45089373HCID 45089373, compound

Conditions

Temperature
105 °C

Procedure

A mixture of 4-acteylamino-2-methyl-3-nitro-benzoic acid (4.8 g, 20.2 mmol) and 6 M HCl (aq) (150 mL) in 120 mL dioxane was stirred for 15 min at 105° C. The mixture was cooled, filtered and washed with water.

Workup

  1. temperatureThe mixture was cooled
  2. filtrationfiltered
  3. washwashed with water

Sources & evidence

ORD record
ord-f44a97351dd1430f9036c18955a4eccd
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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