Dicyclohexylcarbodiimide → HCID 67230261, compound

HRID 1406497Notes

Reaction equation

HRID 1406497 reaction equation
C[O:2][C:3](=[O:13])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH3:11])=[C:6]([NH2:12])[CH:5]=1.[Cl:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[C:16]=1[N:22]=[C:23]=S.C1CCC(N=C=NC2CCCCC2)CC1>CN(C=O)C.[OH-].[Na+].C(O)C>[Cl:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[C:16]=1[NH:22][C:23]1[N:10]([CH3:11])[C:7]2[CH:8]=[CH:9][C:4]([C:3]([OH:13])=[O:2])=[CH:5][C:6]=2[N:12]=1

Participants

7

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 1232391,3-Dichloro-2-isothiocyanatobenzeneHCID 15586064Methyl 3-amino-4-(methylamino)benzoate

Product 1

HCID 67230261HCID 67230261, compound

Reagents, catalysts & solvents 3

HCID 702EthanolSolventHCID 6228DimethylformamideSolventHCID 14798Sodium HydroxideSolvent

Procedure

Prepared analogously to example 113a from 3-amino-4-methylamino-benzoic acid methyl ester and 1,3-dichloro-2-isothiocyanato-benzene with DCC in DMF and NaOH in ethanol.

Sources & evidence

ORD record
ord-e8c8e15d41fe4df3bc8fdc4fbb0f94b8
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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