1,2-Dichloroethane → HCID 67230118, compound

HRID 1406532Notes

Reaction equation

HRID 1406532 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][C:17]=1[NH:18][CH3:19])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([Br:14])=[CH:10][CH:9]=1)=[O:6].[Cl:20][C:21]1[CH:22]=[C:23]([CH:28]=[CH:29][C:30]=1[N:31]=[C:32]=S)[C:24]([O:26][CH3:27])=[O:25].C(Cl)CCl>CN(C=O)C>[Br:14][C:11]1[CH:12]=[CH:13][C:8]([NH:7][C:5]([C:4]2[CH:15]=[CH:16][C:17]3[N:18]([CH3:19])[C:32]([NH:31][C:30]4[CH:29]=[CH:28][C:23]([C:24]([O:26][CH3:27])=[O:25])=[CH:22][C:21]=4[Cl:20])=[N:1][C:2]=3[CH:3]=2)=[O:6])=[CH:9][CH:10]=1

Participants

5

Reactant 3

HCID 111,2-DichloroethaneHCID 39058265HCID 39058265, compoundHCID 67230022HCID 67230022, compound

Product 1

HCID 67230118HCID 67230118, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to example 106a from 3-amino-N-(4-bromophenyl)-4-(methylamino)-benzamide and methyl 3-chloro-4-isothiocyanatobenzoate in DMF with EDC.

Sources & evidence

ORD record
ord-aef4cab49a7648daad6eb371273eac24
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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